5-Amino-1MQ

5-Amino-1-methylquinolinium

Anti-Obesity, Energy

What is 5-AMINO-1?

5-amino-1MQ is a small molecule drug that functions to block the activity of an enzyme called nicotinamide N-methyltransferase (NNMT). NNMT is a cytosolic enzyme that plays a significant role in metabolism and energy and is predominantly active in fat tissue. By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1). SIRT1 is also known as ‘the longevity gene’ because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease,  neurodegeneration, and cancer.

In Layman’s terms

This means that 5-amino-1MQ allows your body to burn fat for energy while maintaining muscle mass preferentially. It is a potentially superior treatment option for individuals suffering from (or who are at risk for) type II diabetes. Furthermore, the activation of SIRT1 by an increase in NAD+ suggests 5-amino-1MQ is a good option for those who want to develop a comprehensive anti-aging protocol.

Benefits of 5-amino 1MQ

• Can reverse diet-induced obesity.
• Can treat related metabolic conditions.
• Can increase cellular energy regulators.
• Can prevent lipogenesis (fat accumulation).
• Can regulate energy expenditure in fat cells.
• Can increase NAD+ and SAM concentrations in fat cells.